Fluorescent-Labeled Recombinant Proteins
Fluorescent-labeled recombinant proteins that allow target molecules to be directly stained and detected by flow cytometry.
Fluorescent-labeled Recombinant Proteins
Fluorescent-labeled proteins are protein molecules that covalently binding with fluorescent dyes. The fluorescent label (fluorescent tag, fluorescent probe) generally acts as a tool to investigate conformational dynamics and molecular interactions or track the movement of proteins in order to gain insight into their biological functions.
Chemsis offers fluorescent-labeled proteins for detecting CARs, immune checkpoint receptors, or SARS-CoV-2-binding cells & information resources. Unlike native proteins, recombinant proteins allow for precise control over modifications, production, and large-scale synthesis tailored to experimental needs.
Fluorokines for Chimeric Antigen Receptor Detection
The ability to evaluate the expression of a chimeric antigen receptor (CAR) following retroviral or lentiviral transduction of a patient’s or donor’s T or natural killer (NK) cells is an important step in the production of CAR-T or CAR-NK cells for cancer immunotherapy. Using fluorescent-labeled proteins, CAR+ cells can be directly stained and detected by flow cytometry, making it easy to evaluate the percentage of transduced cells.
Fluorescent-labeled Proteins for CAR Detection - Products by Molecule
| BCMA | CD19 | CD30/TNFRSF8 | CD40/TNFRSF5 | CD300e/LMIR6 | DLL3 |
| EGF R | EMMPRIN/CD147 | EpCAM/TROP1 | ErbB2/Her2 | Fc gamma RIIA/CD32a (R167) | Fc gamma RIIIA/CD16a |
| Glypican 3 | IL-13 R alpha2 | Mesothelin | MUC-1 | OX40 | PD-1 |
| Siglec-2/CD22 | Siglec-3/CD33 | TRAIL R2 | TSLP R | VEGFR2/KDR |
Fluorokines for Immune Checkpoint Ligands
| B7-1/CD80 | B7-2/CD86 | B7-H2 | B7-H3 | B7-H4 | CD155/PVR |
| GITR Ligand/TNFSF18 | HVEM/TNFRSF14 | IgG1 | PD-L1/B7-H1 | PD-L2/B7-DC | SIRP alpha |
