Office Address

Swami Om Bungalow, Bungalow No.-5, Singhad Road, Opp Bharti Sahakari Bank Ltd, near Shree Nagnath Furniture, Dhayri Phata, Pune – 411041

Phone Number

+91 9850826071

Email Address

info@chemsis.co.in

Fluorescent-Labeled Recombinant Proteins

Fluorescent-labeled recombinant proteins that allow target molecules to be directly stained and detected by flow cytometry.

Fluorescent-labeled Recombinant Proteins

Fluorescent-labeled proteins are protein molecules that covalently binding with fluorescent dyes. The fluorescent label (fluorescent tag, fluorescent probe) generally acts as a tool to investigate conformational dynamics and molecular interactions or track the movement of proteins in order to gain insight into their biological functions.

Chemsis offers fluorescent-labeled proteins for detecting CARs, immune checkpoint receptors, or SARS-CoV-2-binding cells & information resources. Unlike native proteins, recombinant proteins allow for precise control over modifications, production, and large-scale synthesis tailored to experimental needs.

Fluorokines for Chimeric Antigen Receptor Detection

The ability to evaluate the expression of a chimeric antigen receptor (CAR) following retroviral or lentiviral transduction of a patient’s or donor’s T or natural killer (NK) cells is an important step in the production of CAR-T or CAR-NK cells for cancer immunotherapy. Using fluorescent-labeled proteins, CAR+ cells can be directly stained and detected by flow cytometry, making it easy to evaluate the percentage of transduced cells.

Fluorescent-labeled Proteins for CAR Detection - Products by Molecule

BCMA CD19 CD30/TNFRSF8 CD40/TNFRSF5 CD300e/LMIR6 DLL3
EGF R EMMPRIN/CD147 EpCAM/TROP1 ErbB2/Her2 Fc gamma RIIA/CD32a (R167) Fc gamma RIIIA/CD16a
Glypican 3 IL-13 R alpha2 Mesothelin MUC-1 OX40 PD-1
Siglec-2/CD22 Siglec-3/CD33 TRAIL R2 TSLP R VEGFR2/KDR  

Fluorokines for Immune Checkpoint Ligands

B7-1/CD80 B7-2/CD86 B7-H2 B7-H3 B7-H4 CD155/PVR
GITR Ligand/TNFSF18 HVEM/TNFRSF14 IgG1 PD-L1/B7-H1 PD-L2/B7-DC SIRP alpha